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Rockies Rock Red Sox

Boston Red Sox second baseman Dustin Pedroia throws to first base in the third inning of a baseball game against the Colorado Rockies on Tuesday, Sept. 24, 2013 in Denver. (AP Photo/Chris Schneider)

Boston Red Sox second baseman Dustin Pedroia throws to first base in the third inning of a baseball game against the Colorado Rockies on Tuesday, Sept. 24, 2013 in Denver. (AP Photo/Chris Schneider)

Denver — Charlie Blackmon hit his first career leadoff homer and Tyler Chatwood pitched seven strong innings, lifting the Colorado Rockies to an 8-3 victory over the Boston Red Sox on Tuesday night.

John Lackey (10-13) struggled on the road again, allowing four runs and six hits in six innings. The right-hander is 1-5 away from Fenway Park since the All-Star break.

Lackey also gave up solo homers to Troy Tulowitzki and Corey Dickerson.

Chatwood (8-5) shut down a potent Red Sox lineup as he gave up one unearned run and three hits before being pulled for a pinch hitter with a 4-1 lead in the seventh.

The Rockies went on to score four times that inning to seal the win, with DJ LeMahieu and Michael Cuddyer each delivering two-run singles.

Cuddyer finished the night 2 for 4 with a double to raise his average to an NL-best .335.

With the AL East title wrapped up, the Red Sox are now focused on securing the best record in the league. They were holding onto a slim one-game lead over Oakland heading into the night.

Manager John Farrell also is using these last few games as a way figure out his final postseason roster spots. Farrell said there are a couple still up for grabs.

David Ortiz played first base instead of Mike Napoli without the use of a designated hitter. Ortiz showed off his glove, too, snaring a scorching liner from Dickerson to end the sixth.

Chatwood pitched carefully to the dangerous Ortiz, even intentionally walking him in first with a runner on second. The ploy worked as Jarrod Saltalamacchia grounded out.

Later, Ortiz hit a fly to the deepest part of the park, but Blackmon tracked it down.

The only mistake Chatwood made wasn’t on the mound but covering first base in the seventh. With two outs and Will Middlebrooks on second, Todd Helton made a diving stop on Jackie Bradley Jr.’s grounder and quickly flipped it to Chatwood, who dropped the ball before stepping on the base.

Chatwood scooped it up and threw wide to home plate and into the Red Sox dugout, allowing Middlebrooks to score. Chatwood was charged with two errors on the play and Bradley advanced to third.

But Chatwood escaped more damage when his wild pitch bounced off the wall behind home plate, allowing catcher Jordan Pacheco to quickly field the ball and flick it to Chatwood, who tagged out Bradley, keeping the score 4-1.

Saltalamacchia hit a two-run homer in the ninth after Ortiz singled.

Notes: Red Sox OF Jacoby Ellsbury (right foot) could return to the lineup as soon as today.

Rays 7, Yankees 0

New York — Matt Moore had New York flailing for five wild innings, and Tampa Bay beat the Yankees to push them to the brink of missing out on the postseason for the second time in 19 years.

Tampa Bay roughed up Hiroki Kuroda in tightening its grip on an AL wild-card spot with its fifth straight win. Matt Joyce had a leadoff homer as the Rays jumped ahead 3-0 in the first and David DeJesus had two RBI doubles.

Tampa Bay has a one-game lead over Cleveland for the top wild card with five to play. Texas and Kansas City played later.

The Yankees trail the Indians, who won 5-4, by five games — and also are behind the Rangers and Royals. The Yankees would be eliminated today if Cleveland wins and the Yankees lose.

Indians 5, White Sox 4

Cleveland — Pinch-hitter Jason Giambi belted a two-run homer with two outs in the ninth inning to give Cleveland a stunning win over Chicago, keeping the Indians up with the lead pack in the AL wild-card race.

Giambi drove a 1-1 pitch from Addison Reed (5-4) into the lower deck in right field to save the Indians from a potentially devastating loss. Giambi’s shot bailed out controversial closer Chris Perez, who gave up two homers in the top of the ninth.

Blue Jays 3, Orioles 2 (10)

Baltimore — Toronto eliminated Baltimore from the playoff hunt Tuesday night, using two clutch RBI singles by Mark DeRosa to beat the Orioles in 10 innings.

Baltimore’s sixth straight loss, combined with Cleveland’s comeback win over the Chicago White Sox, left the Orioles six games behind the Indians for the final wild-card slot with five games left.

Cardinals 2, Nationals 0

St. Louis — Cardinals rookie Michael Wacha lost his no-hit bid on Ryan Zimmerman’s infield single with two outs in the ninth inning, and St. Louis beat Washington to close in on the NL Central title.

Making his ninth career start, Wacha came about as close as possible to finishing off the third no-hitter in the majors this season. Instead, he became the third pitcher to have a bid broken up with one out to go.

Braves 3, Brewers 2

Atlanta — Andrelton Simmons’ single to the gap in right-center drove in Justin Upton with two outs in the ninth inning to give the Atlanta a win over Milwaukee.

Mets 4, Reds 2

Cincinnati — Daniel Murphy hit a three-run homer off Mike Leake, whose long streak of scoreless innings got shattered early, and New York beat Cincinnati, a costly setback to the Reds’ hopes of a second straight NL Central title.

Phillies 2, Marlins 1

Miami — Darin Ruf and Kevin Frandsen drove in runs without a hit in the first inning, and Philadelphia beat Miami to hand the Marlins their 100th loss of the season.

Notes

■ Orioles third baseman Manny Machado got some good news: He has a torn ligament in his left knee and could be running again six to eight weeks because his ACL and MCL ligaments are fine.

An MRI on Tuesday revealed Machado has a torn medial patellofemoral ligament. The Orioles hope he can recover without having surgery.

The injury occurred Monday during Baltimore’s game at Tampa Bay. Machado was running out a single and stepped awkwardly on the inside of the base. He tumbled to the ground and had to be taken off the field on a stretcher.

The Orioles feared Machado tore his ACL, which would have kept him sidelined into the 2014 season.

Machado had played in every game this season and was an integral part of team’s success.